S-adenosylhomocysteine hydrolase (SAHH)
SAHH
S-adenosylhomocysteine hydrolase (SAHH) is an NAD+ dependent tetrameric enzyme that catalyzes the hydrolysis of S-adenosylhomocysteine to adenosine and homocystein, participates in the methionine, transsulfurization and transmethylation metabolic pathways, regulates the intracellular levels of homocysteine and adenosine, and thus affecting various aspects of biological metabolism. S-adenosylhomocysteine hydrolase regulates the gene expression and cell growth. S-adenosylhomocysteine hydrolase is related to virus infection, parasite growth like Leishmania, and hyperhomocysteinemia such as atherosclerotic vascular disease and thromboembolic disease[1].
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S-adenosylhomocysteine hydrolase (SAHH) Related Products (9)
Related Products (9)
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3-Deazaneplanocin A
0 ImagesSynonyms: DZNep; 3-Deazaneplanocin3-Deazaneplanocin A (DZNep) is a potent histone methyltransferase EZH2 inhibitor. 3-Deazaneplanocin A is a potent S-adenosylhomocysteine hydrolase (AHCY) inhibitor. 3-Deazaneplanocin A shows anti-orthopoxvirus activity.
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3-Deazaneplanocin A hydrochloride
0 ImagesSynonyms: DZNep hydrochloride; NSC 617989 hydrochloride; 3-Deazaneplanocin hydrochloride3-Deazaneplanocin A hydrochloride (DZNep hydrochloride) is a potent histone methyltransferase EZH2 inhibitor. 3-Deazaneplanocin A hydrochlorideis a potent S-adenosylhomocysteine hydrolase (AHCY) inhibitor. 3-Deazaneplanocin A hydrochloride also has anti-orthopoxvirus and anti-variola activities.
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3-Deazaadenosine
0 Images3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 μM; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti-HIV activity.
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Adenosine dialdehyde
0 ImagesAdenosine dialdehyde, a purine nucleoside analogue, is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM). Adenosine Dialdehyde exhibits potent anti-tumor activity in vivo and can be used for the cancer research.
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3-Deazaadenosine hydrochloride
0 Images3-Deazaadenosine (hydrochloride) is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 μM; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti-HIV activity.
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Aristeromycin
0 ImagesAristeromycin, an adenosine analog, is an antibiotic and a potent S-adenosylhomocysteine hydrolase (AHCY) inhibitor.
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SAHH-IN-1
0 ImagesCat. No.: HY-W002968CAS No.: 946-99-6SAHH-IN-1 (Compound 4) is an inhibitor of S-adenosylhomocysteine hydrolase (SAHH), with an IC50 of 814 nM. SAHH-IN-1 can be used for the study of age-related degenerative diseases (such as Alzheimer's disease).
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Adenosine dialdehyde (Standard)
0 ImagesCat. No.: HY-123055RCAS No.: 34240-05-6Adenosine dialdehyde (Standard) is the analytical standard of Adenosine dialdehyde. This product is intended for research and analytical applications. Adenosine dialdehyde, a purine nucleoside analogue, is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM). Adenosine Dialdehyde exhibits potent anti-tumor activity in vivo and can be used for the cancer research.
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3-Deazaneplanocin A (Standard)
0 ImagesCat. No.: HY-10442RCAS No.: 102052-95-9Synonyms: DZNep (Standard); 3-Deazaneplanocin (Standard)3-Deazaneplanocin A (Standard) is the analytical standard of 3-Deazaneplanocin A (HY-10442). This product is intended for research and analytical applications. 3-Deazaneplanocin A (DZNep) is a potent histone methyltransferase EZH2 inhibitor. 3-Deazaneplanocin A is a potent S-adenosylhomocysteine hydrolase (AHCY) inhibitor. 3-Deazaneplanocin A shows anti-orthopoxvirus activity.
